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Management of Metastatic Spinal Cord Compression.
- Source :
-
Southern Medical Journal . Sep2017, Vol. 110 Issue 9, p586-593. 8p. - Publication Year :
- 2017
-
Abstract
- Cancer metastasis is a key event in tumor progression associated not only with mortality but also significant morbidity. Metastatic disease can promote end-organ dysfunction and even failure through mass effect compression of various vital organs including the spinal cord. In such cases, prompt medical attention is needed to restore neurological function, relieve pain, and prevent permanent damage. The three therapeutic approaches to managing metastatic spinal cord compression include corticosteroids, surgery, and radiation therapy. Although each may improve patients' symptoms, their combination has yielded the best outcome. In cancer patients with clinical suspicion of spinal cord compression, dexamethasone should be initiated followed by surgical decompression, when possible, and radiation. The latter becomes the preferred treatment in patients with inoperable disease. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CANCER treatment
*METASTASIS
*SPINAL cord compression
*CANCER pain
*ADRENOCORTICAL hormones
*HORMONE therapy
*STEREOTACTIC radiotherapy
*ANTI-inflammatory agents
*DEXAMETHASONE
*COMBINED modality therapy
*RADIOTHERAPY
*SPINAL tumors
*SURGICAL decompression
*DISEASE complications
TREATMENT of spinal cord compression
Subjects
Details
- Language :
- English
- ISSN :
- 00384348
- Volume :
- 110
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Southern Medical Journal
- Publication Type :
- Academic Journal
- Accession number :
- 124956314
- Full Text :
- https://doi.org/10.14423/SMJ.0000000000000700