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Candidemia in the Neonatal Intensive Care Unit: A Retrospective, Observational Survey and Analysis of Literature Data.
- Source :
-
BioMed Research International . 8/13/2017, Vol. 2017, p1-12. 12p. - Publication Year :
- 2017
-
Abstract
- We evaluated the epidemiology of Candida bloodstream infections in the neonatal intensive care unit (NICU) of an Italian university hospital during a 9-year period as a means of quantifying the burden of infection and identifying emerging trends. Clinical data were searched for in the microbiological laboratory database. For comparative purposes, we performed a review of NICU candidemia. Forty-one candidemia cases were reviewed (overall incidence, 3.0 per 100 admissions). Candida parapsilosis sensu stricto (58.5%) and C. albicans (34.1%) were the most common species recovered. A variable drift through years was observed; in 2015, 75% of the cases were caused by non-albicans species. The duration of NICU hospitalization of patients with non-albicans was significantly longer than in those with C. albicans (median days, 10 versus 12). Patients with non-albicans species were more likely to have parenteral nutrition than those with C. albicans (96.3% versus 71.4%). Candida albicans was the dominant species in Europe and America (median, 55% and 60%; resp.); non-albicans species predominate in Asia (75%). Significant geographic variation is evident among cases of candidemia in different parts of the world, recognizing the importance of epidemiological data to facilitate the treatment. [ABSTRACT FROM AUTHOR]
- Subjects :
- *INFECTION
*ACADEMIC medical centers
*ANTIFUNGAL agents
*BIRTH weight
*LOW birth weight
*BLOOD testing
*BLOODBORNE infections
*CANDIDA albicans
*CELL culture
*CHI-squared test
*DATABASES
*ETHICS
*FISHER exact test
*GESTATIONAL age
*HOSPITAL care
*LENGTH of stay in hospitals
*INFORMED consent (Medical law)
*MEDLINE
*NEONATAL intensive care
*PATHOGENIC microorganisms
*POLYMERASE chain reaction
*SURVEYS
*LITERATURE reviews
*NEONATAL intensive care units
*HUMAN research subjects
*RETROSPECTIVE studies
*DATA analysis software
*DESCRIPTIVE statistics
*CANDIDEMIA
*MANN Whitney U Test
*DIAGNOSIS
Subjects
Details
- Language :
- English
- ISSN :
- 23146133
- Volume :
- 2017
- Database :
- Academic Search Index
- Journal :
- BioMed Research International
- Publication Type :
- Academic Journal
- Accession number :
- 124587758
- Full Text :
- https://doi.org/10.1155/2017/7901763