Highly chemoselective reduction of azides to amines by Fe(0) nanoparticles in water at room temperature.

Authors :: Panja, Subir
kundu, Debasish
Ahammed, Sabir
Ranu, Brindaban C.
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Aug2017, Vol. 58 Issue 35, p3457-3460. 4p.
Publication Year :: 2017
Abstract: A highly chemoselective reduction of aryl, heteroaryl, acyl and sulfonyl azides to the corresponding amines has been achieved by Fe(0) nanoparticles in water at room temperature in the absence of external hydride source. Several readily reducible functionalities including alkene, alkyne, S-S linkage, OTBDMS remain unaffected during reduction. [ABSTRACT FROM AUTHOR]

Subjects :: *CHEMOSELECTIVITY
*AZIDES
*IRON in water
*AMINES
*CHEMICAL reduction
*METAL nanoparticles

Language :: English
ISSN :: 00404039
Volume :: 58
Issue :: 35
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 124491088
Full Text :: https://doi.org/10.1016/j.tetlet.2017.07.076

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