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Estrogen receptor ligands. Part 1: The discovery of flavanoids with subtype selectivity
- Source :
-
Bioorganic & Medicinal Chemistry Letters . Mar2004, Vol. 14 Issue 6, p1417. 5p. - Publication Year :
- 2004
-
Abstract
- A class of flavanoids exhibiting a high degree of selectivity for ERα over ERβ has been discovered. The most active analogue 6 was found to be 66-fold ERα-selective and demonstrated uterine estradiol antagonism. [Copyright &y& Elsevier]
- Subjects :
- *ESTROGEN
*SEX hormones
*STEROID hormones
*HYSTEROSCOPY
Subjects
Details
- Language :
- English
- ISSN :
- 0960894X
- Volume :
- 14
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Bioorganic & Medicinal Chemistry Letters
- Publication Type :
- Academic Journal
- Accession number :
- 12433655
- Full Text :
- https://doi.org/10.1016/j.bmcl.2004.01.031