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Pup recycling regulates the proteasome.
- Source :
-
FEBS Journal . Jun2017, Vol. 284 Issue 12, p1787-1789. 3p. - Publication Year :
- 2017
-
Abstract
- The Pup proteasome system (PPS) in bacteria is equivalent to the eukaryotic ubiquitin proteasome system (UPS) that allows controlled protein degradation. Unlike the UPS, however, the PPS machinery and regulation is still poorly understood. In this issue of The FEBS Journal, Gur and colleagues combine experimental and modelling analyses to show how the PPS maintains steady‐state levels of protein pupylation and consequently tightly controlled protein degradation. [ABSTRACT FROM AUTHOR]
- Subjects :
- *PROTEASOMES
*PROTEIN synthesis
*PROTEOLYSIS
*MYCOBACTERIUM tuberculosis
*UBIQUITIN
Subjects
Details
- Language :
- English
- ISSN :
- 1742464X
- Volume :
- 284
- Issue :
- 12
- Database :
- Academic Search Index
- Journal :
- FEBS Journal
- Publication Type :
- Academic Journal
- Accession number :
- 123670899
- Full Text :
- https://doi.org/10.1111/febs.14112