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Long-term outcomes of Heller's myotomy and balloon dilatation in childhood achalasia.

Authors :
Thapar, Nikhil
Saliakellis, Efstratios
Cristofori, Fernanda
Lindley, Keith
Borrelli, Osvaldo
Roebuck, Derek
Cross, Kate
Kiely, Edward
Curry, Joseph
Source :
European Journal of Pediatrics. Jul2017, Vol. 176 Issue 7, p899-907. 9p. 3 Charts, 1 Graph.
Publication Year :
2017

Abstract

Achalasia is a rare esophageal motility disorder: its optimal treatment in children is still a matter of debate. Records of children treated for achalasia, over an 18-year period, were reviewed.Forty-eight children (median age at diagnosis 10 years; range 3-17 years) were identified. Twenty-eight patients were initially treated with Heller's myotomy (HM) and 20 with balloon dilatation (BD). At last follow-up (median 3 years; range 1-5.5 years), 43.8% (21/48) of children were symptom free. The number of asymptomatic children was significantly higher among those treated initially with HM compared to BD (HM 15/28, 53.6% BD 6/20, 30%, p < 0.05). All children who underwent BD required HM due to symptom recurrence. The median (range) total number of procedures was significantly higher in the BD group (BD 3 (1-7); HM 1 (1-5); p < 0.05) with a shorter time to the second intervention (BD 14 months, 95%CI 4-24; HM 58 months, 95%CI 38-79; p < 0.05). Of 108 procedures, esophageal perforation occurred in two children after HM (two out of 48 HM procedures in total, 4%) and one child after BD (1/60, 1.7%).<bold>Conclusion: </bold>Less than half of children with achalasia are symptom free after initial treatment with either BD or HM. HM, however, when performed as first procedure, provided longer symptom-free period and reduced need for subsequent intervention. What is Known: • Balloon dilatation (BD) and Heller's myotomy (HM) are safe and effective treatment options for achalasia. • Controversy, however, exists regarding the most effective initial therapeutic approach. What is New: • HM with or without fundoplication may represent the initial therapeutic approach of choice. • Initial BD may negatively affect the outcome of a subsequent HM. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03406199
Volume :
176
Issue :
7
Database :
Academic Search Index
Journal :
European Journal of Pediatrics
Publication Type :
Academic Journal
Accession number :
123670472
Full Text :
https://doi.org/10.1007/s00431-017-2924-x