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Mammary fibroadenomatoid hyperplasia in a heifer.
Mammary fibroadenomatoid hyperplasia in a heifer.
- Source :
-
Ciência Rural . 2017, Vol. 47 Issue 6, p1-5. 5p. - Publication Year :
- 2017
-
Abstract
- This manuscript described the anatomopathological and immunohistochemical findings in a rare case of mammary fibroadenomatoid hyperplasia in a 12-month-old Holstein heifer. A yellow, multilobulated, firm 20cm x 9cm x 6.5cm mass affecting the right quarters of the udder was observed. Total mastectomy was performed. Microscopic evaluation revealed severe hyperplasia of the mammary epithelium and numerous well-differentiated and mildly pleomorphic acini. Additionally, moderate proliferation of the fibrous connective tissue and the myoepithelial cells near the proliferating acini was evident. About 50% of the proliferating epithelial cells showed positive nuclear labeling for estrogen and progesterone receptors, and approximately one-third were positive for Ki-67. In addition, the myoepithelial cells exhibited diffuse nuclear immunoreactivity for p63. Based on the clinical, morphologic, and immunohistochemical findings, a diagnosis of mammary fibroadenomatoid hyperplasia with probable influence of ovarian steroids was made. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01038478
- Volume :
- 47
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Ciência Rural
- Publication Type :
- Academic Journal
- Accession number :
- 123121119
- Full Text :
- https://doi.org/10.1590/0103-8478cr20160943