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Mammary fibroadenomatoid hyperplasia in a heifer.

Mammary fibroadenomatoid hyperplasia in a heifer.

Authors :
Silva, Lorena Ferreira
Franco da Silva, Luiz Antonio
Rabelo, Rogério Elias
Rodrigues da Silva, Wanessa Patrícia
Dantas Cassali, Geovanni
De Biasi Bassani Gonçalves, Aline
Ferreira de Sant'Ana, Fabiano José
Source :
Ciência Rural. 2017, Vol. 47 Issue 6, p1-5. 5p.
Publication Year :
2017

Abstract

This manuscript described the anatomopathological and immunohistochemical findings in a rare case of mammary fibroadenomatoid hyperplasia in a 12-month-old Holstein heifer. A yellow, multilobulated, firm 20cm x 9cm x 6.5cm mass affecting the right quarters of the udder was observed. Total mastectomy was performed. Microscopic evaluation revealed severe hyperplasia of the mammary epithelium and numerous well-differentiated and mildly pleomorphic acini. Additionally, moderate proliferation of the fibrous connective tissue and the myoepithelial cells near the proliferating acini was evident. About 50% of the proliferating epithelial cells showed positive nuclear labeling for estrogen and progesterone receptors, and approximately one-third were positive for Ki-67. In addition, the myoepithelial cells exhibited diffuse nuclear immunoreactivity for p63. Based on the clinical, morphologic, and immunohistochemical findings, a diagnosis of mammary fibroadenomatoid hyperplasia with probable influence of ovarian steroids was made. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
01038478
Volume :
47
Issue :
6
Database :
Academic Search Index
Journal :
Ciência Rural
Publication Type :
Academic Journal
Accession number :
123121119
Full Text :
https://doi.org/10.1590/0103-8478cr20160943