New pathways in the treatment for menopausal hot flushes.

The article discusses discovery of new pathways in treatment of menopausal hot flushes. Topics include characteristics of hot flushes, or vasomotor symptoms, which are experienced by a significant percentage of postmenopausal women, and cause sleep disturbances, fatigue, and decreased cognitive function; oestrogen deficiency; and placebo-controlled trial studying the oral neurokinin 3 receptor (NK3R) antagonist MLE4901 as a new therapy for menopausal hot flushes, published in the journal.