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Optimization of Aflatoxin B1 Aptasensing.
- Source :
-
Journal of Toxicology . 5/14/2017, p1-6. 6p. - Publication Year :
- 2017
-
Abstract
- Combination of aptamers with DNAzymes attracted intense attention for development of DNA-based biosensors for detection of mycotoxins. In the present study a combination of aflatoxin B1 specific aptamer and HRP- (horseradish peroxidase-) mimicking DNAzyme was optimized for detecting aflatoxin B1. Detecting approach is based on the binding affinity of aflatoxin B1 to its specific aptamer and conversion of substrate to a detectable colorimetric signal by a linked DNAzyme. Compared to conventional methods for aflatoxin B1 detection, DNA-based assay has the advantages of low cost, long-term stability, and rapid, simple, and user-friendly steps. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 16878191
- Database :
- Academic Search Index
- Journal :
- Journal of Toxicology
- Publication Type :
- Academic Journal
- Accession number :
- 123026951
- Full Text :
- https://doi.org/10.1155/2017/2461354