经皮穴位电刺激对甲状腺手术后围拔管期应激反应的影响.

Objective: To investigate the effects of transcutaneous electrical acupoint stimulation (TEAS) on stress response during extubation of general anesthesia in patients undergoing thyroidectomy. Methods: Sixty patients, ASA I ～II, undergoing thyroidectomy under general anesthesia were randomly divided into 2 groups (n=30 each) using a random number table: transcutaneous electrical acupoint stimulation group (T group) and Sham stimulation group (C group). 30 mnins prior to the induction of anesthesia, patients in T group were given electrical stimulation, patients in C group had the electrodes applied, but received no stimulation.Baseline (T0), at the end of operation (T1), immediately after extubation (T2),and at 5, 10 min after extubation (T3, T4) noninvasive arterial blood pressure (NIBP), mean arterial pressure (MAP) and heart rate (HR) were recorded. Blood samples were taken from the vein artery at T0～T4 to record the concentration of Epinephrine (E), Norepinephrine (NE) and Cortisone (Cor). The extubation quality score, Ricker sedation-agitation scale, were also recorded and analyzed. Results: Compared with the baseline value at T0, NIBP, MAP, HR were significantly increased at T2～T4 in both groups (P＜0.05); The NIBP, MAP, HR and concentrations of E, NE, Cor in T group were lower than those in C group at T2～T4 (P＜0.05); Compared with C group, the extubation quality score and the Ricker sedation-agitation scale was lower (P＜0.05). Conclusions: Transcutaneous electrical acupoint stimulation could restrain the stress response during extubation of general anesthesia in patients undergoing thyroidectomy, and be conducive to maintain the hemodynamics stability. [ABSTRACT FROM AUTHOR]