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Alkynylation of cyclopropyl trifluoromethyl ketone catalyzed by CuF2ยท2H2O/4,7-diphenyl-1,10-phenanthroline.
- Source :
-
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry . Apr2017, Vol. 58 Issue 16, p1564-1567. 4p. - Publication Year :
- 2017
-
Abstract
- CuF 2 ·2H 2 O/4,7-diphenyl-1,10-phenanthroline was found to be a highly efficient catalyst for the nucleophilic alkynylation of cyclopropyl trifluoromethyl ketone. The corresponding trifluoromethyl-substituted tertiary propargyl alcohols were synthesized in moderate to excellent yields under mild conditions. The catalyst system could also be applied to aromatic trifluoromethyl ketone as well as trifluoropyruvate. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00404039
- Volume :
- 58
- Issue :
- 16
- Database :
- Academic Search Index
- Journal :
- Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 122241084
- Full Text :
- https://doi.org/10.1016/j.tetlet.2017.03.010