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Impact of the functional CD5 polymorphism A471V on the response of chronic lymphocytic leukaemia to conventional chemotherapy regimens.
- Source :
-
British Journal of Haematology . Apr2017, Vol. 177 Issue 1, p147-150. 4p. 1 Chart, 1 Graph. - Publication Year :
- 2017
-
Abstract
- The article discusses the impact of functionally relevant germline CD5 variants on the prognosis of chronic lymphocytic leukaemia (CLL). CD5 variants were found to have influenced the natural behavior of CLL cell biology and its outcome. CD5 signalling was also considered a relevant factor for the production of B1a cell autocrine growth factor interleukin 10.
Details
- Language :
- English
- ISSN :
- 00071048
- Volume :
- 177
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- British Journal of Haematology
- Publication Type :
- Academic Journal
- Accession number :
- 122099650
- Full Text :
- https://doi.org/10.1111/bjh.14037