Kinetics of cytochromes P-450 IA1 and IIB1 in reconstituted systems with dilauroyl- and distearoyl-glycerophosphocholine.

Authors :: Balvers, Walter G.
Boersma, Marelle G.
Veeger, Cees
Rietjens, Ivonne M.C.M.
Source :: European Journal of Biochemistry. 7/15/93, Vol. 215 Issue 2, p373-381. 9p.
Publication Year :: 1993
Abstract: Investigates the effect of changing the fatty acyl moiety of phosphatidylcholine from dilauroyl to distearoyl on the kinetic parameters of O-dealkylation of alkoxyresorufins and ethoxycoumarin dependent on reconstituted cytochromes P-450 IA1 and IIB1. Role of the cytochrome P-450 enzyme system in the monooxygenation of a broad range of endogenous substrates and xenobiotics.

Subjects :: *LECITHIN
*CYTOCHROMES
*ENZYMES
*XENOBIOTICS
*CHARGE exchange
*BIOCHEMISTRY

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