Back to Search
Start Over
Dangerous Liaisons: Deviant Endothelium NOTCHes toward Tumor Metastasis.
- Source :
-
Cancer Cell . Mar2017, Vol. 31 Issue 3, p301-303. 3p. - Publication Year :
- 2017
-
Abstract
- In this issue of Cancer Cell , Wieland et al. uncover a feedback loop in which tumor cells, by augmenting Notch signaling, provoke a senescent and pro-inflammatory state in endothelial cells, promoting neutrophil infiltration, tumor cell adhesion, and metastasis. Interfering with this Notch-dependent crosstalk may be a therapeutic approach to block metastasis. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 15356108
- Volume :
- 31
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Cancer Cell
- Publication Type :
- Academic Journal
- Accession number :
- 121673877
- Full Text :
- https://doi.org/10.1016/j.ccell.2017.02.016