Systemic allergic contact dermatitis caused by methyl aminolaevulinate in a patient with keratosis-ichthyosis-deafness syndrome.

The article presents a case study of a 53-year-old female with keratosis-ichthyosis-deafness (KID) syndrome and a long history of extensive hypertrophic lesions on both legs. The patient was diagnosed with systemic allergic contact dermatitis caused by methyl aminolaevulinate from Metvixia, a topical drug applied exclusively on legs. Results of different photopatch tests performed in the patient and the immediate side-effects of photodynamic therapy are discussed.