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Physical inactivity is a strong risk factor for stroke in the oldest old: Findings from a multi-ethnic population (the Northern Manhattan Study).
- Source :
-
International Journal of Stroke . Feb2017, Vol. 12 Issue 2, p197-200. 4p. - Publication Year :
- 2017
-
Abstract
- Background: The fastest growing segment of the population is those age ⩾80 who have the highest stroke incidence. Risk factor management is complicated by polypharmacy-related adverse events. Aims: To characterize the impact of physical inactivity for stroke by age in a multi-ethnic prospective cohort study (NOMAS, n =3298). Methods: Leisure time physical activity was assessed by a validated questionnaire and our primary exposure was physical inactivity (PI). Participants were followed annually for incident stroke. We fit Cox-proportional hazard models to calculate hazard ratios and 95% confidence intervals (HR 95% CI) for the association of PI and other risk factors with risk of stroke including two-way interaction terms between the primary exposures and age (<80 vs. ⩾80). Results: The mean age was 69±10.3 years and 562 (17%) were ⩾80 at enrolment. PI was common in the cohort (40.8%). Over a median of 14 years, we found 391 strokes. We found a significant interaction of age ⩾80 on the risk of stroke with PI (p=0.03). In stratified models, PI versus any activity (adjusted HR 1.60, 95%CI 1.05-2.42) was associated with an increased risk of stroke among those ⩾80. Conclusion: Physical inactivity is a treatable risk factor for stroke among those older than age 80. Improving activity may reduce the risk of stroke in this segment of the population. [ABSTRACT FROM AUTHOR]
- Subjects :
- *SEDENTARY behavior
*POLYPHARMACY
*HEALTH of older people
STROKE risk factors
Subjects
Details
- Language :
- English
- ISSN :
- 17474930
- Volume :
- 12
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- International Journal of Stroke
- Publication Type :
- Academic Journal
- Accession number :
- 121096270
- Full Text :
- https://doi.org/10.1177/1747493016676614