Cycloadditions of o-quinone dimethides with p-quinol derivatives: regiocontrolled formation of anthracyclic ring systems

Authors :: Wang, Junhua
Pettus, Liping H.
Pettus, Thomas R.R.
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Feb2004, Vol. 45 Issue 8, p1793. 4p.
Publication Year :: 2004
Abstract: Regioselective cycloadditions between the cyclohexadienones 12–14 and the ortho-quinone dimethide 19, which is thermally generated from the corresponding 1,3-dihydro-1-methoxy-2,2-dioxide benzo[c]thiophene 27, are reported. The synthetic sequence provides rapid access to highly substituted anthracyclic system and may be of use for construction of the natural product (+)-rishirilide B. [Copyright &y& Elsevier]

Subjects :: *RING formation (Chemistry)
*CHEMICAL reactions
*ANTHRACYCLINES
*THIOPHENES

Language :: English
ISSN :: 00404039
Volume :: 45
Issue :: 8
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 12096661
Full Text :: https://doi.org/10.1016/j.tetlet.2003.12.114

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