First example of the synthesis of S, O-macroheterocycle based on 2(5 H)-furanone and 2,2´-oxydiethanethiol.

A base-catalyzed reaction of 3,4-dichloro-5-methoxy- and 3,4-dichloro-5-ethoxy-2(5 H)-furanones with 2,2´-oxydiethanethiol gave thiols and bis-thioethers of 2(5 H)-furanone series. A new S, O-macroheterocyclic compound containing a 18-membered oxathiamacrocycle and two 2(5 H)-furanone fragments was synthesized based on the thiols in an aqueous solution of potassium hydroxide, which was characterized by X-ray diffraction. [ABSTRACT FROM AUTHOR]