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Commiphoranes A-D, Carbon Skeletal Terpenoids from Resina Commiphora.
- Source :
-
Organic Letters . Jan2017, Vol. 19 Issue 1, p286-289. 4p. - Publication Year :
- 2017
-
Abstract
- Commiphoranes A-D (1-4), four novel aromatic terpenoids with unprecedented carbon skeletons, were isolated from Resina Commiphora. Their structures were identified by spectroscopic and crystallographic methods. Compounds 1 and 2 are dinorditerpenoids characteristic of a 6/6/6/6 ring system. In contrast, compounds 3 and 4 are sesquiterpenoids possessing a 5/6/7 backbone. Biological evaluation reveals that 3 could significantly attenuate overproduction of fibronectin, collagen I, and α-SMA in TGF-β1-induced rat renal proximal tubular cells. [ABSTRACT FROM AUTHOR]
- Subjects :
- *TERPENES
*COMMIPHORA
*AROMATIC compounds
*SPECTRUM analysis
*CRYSTALLOGRAPHY
Subjects
Details
- Language :
- English
- ISSN :
- 15237060
- Volume :
- 19
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Organic Letters
- Publication Type :
- Academic Journal
- Accession number :
- 120666026
- Full Text :
- https://doi.org/10.1021/acs.orglett.6b03661