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Dimericbiscognienyne A: A Meroterpenoid Dimer from Biscogniauxia sp. with New Skeleton and Its Activity.
- Source :
-
Organic Letters . Jan2017, Vol. 19 Issue 1, p38-41. 334p. - Publication Year :
- 2017
-
Abstract
- Dimericbiscognienyne A (1), an unusual diisoprenyl-cyclohexene-type meroterpenoid dimer, was isolated from Biscogniauxia sp. together with three new monomeric diisoprenyl-cyclohexene-type meroterpenoids (2-4) and one new isoprenyl-benzoic acid-type meroterpenoid (5). All structures were determined by extensive NMR spectroscopic methods, quantum chemical calculations, chemical derivatization, and X-ray crystallography. The formation of 1 is related to a unique intermolecular redox coupling Diels-Alder adduct reaction. Their cytotoxicities and short-term memory enhancement activities against Alzheimer's disease were assessed. [ABSTRACT FROM AUTHOR]
- Subjects :
- *TERPENES
*DIMERS
*XYLARIACEAE
*CYCLOHEXENE
*NUCLEAR magnetic resonance spectroscopy
Subjects
Details
- Language :
- English
- ISSN :
- 15237060
- Volume :
- 19
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Organic Letters
- Publication Type :
- Academic Journal
- Accession number :
- 120665964
- Full Text :
- https://doi.org/10.1021/acs.orglett.6b03264