AVALIAÇÃO DOS EFEITOS DA INFUSÃO DAS FOLHAS DE SYZYGIUM CUMINI EM UM MODELO EXPERIMENTAL DE RESISTÊNCIA À INSULINA EM DROSOPHILA MELANOGASTER.

Introduction: the use of plants as a therapeutic resource is a very ancient practice, and has since been the subject of studies. In this context there is jambolan (Syzygiumcumini) whichis a plant belonging to the family Mirtaceae. The leave shave substance swith anti diabetic action, acting hypoglycemic function, mimicking the actions of insulin, regulating blood glucose levels. Objective: the aim of this study was to evaluate the antioxidant activityof the leaves of Syzygium cumini and the effects of this infusion on a diet enriched experimental model with high glucose concentrations in Drosophila melanogaster. Methods: to verify jambolan the antioxidant used the DPPH (2,2-diphenyl-1picrilhidrazila) second Brand - Williams et al (1995).. The Drosophila were separated by sex, weighed and treated with infusion jambolan leaves except for the control, for three days and on the fourth day were sacrificed and weighed to biochemistry Glucose PAP Liquiform enzymatic triglycerides (Labtest). Results and discussion: regarding males, jambolan effect was highly significant as a protective factor in the diet with 20% sucroseandalso in the diet with 30% sucrose. Conclusion: this study demonstrated that exposure to a high-carbohydrate diet was harmful to D. melanogaster and the Syzygiumtea cumini (jambolan) had a positive effecton glucose and triglycerides parameters, validating this invertebrate model as a tool for the investigation of Diabetes mellitus. [ABSTRACT FROM AUTHOR]