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Acid resistant zirconium phosphate for the long term application of 68Ge/68Ga generator system.
- Source :
-
Applied Radiation & Isotopes . Dec2016, Vol. 118, p343-349. 7p. - Publication Year :
- 2016
-
Abstract
- The 68 Ge/ 68 Ga generator system is an excellent source for producing ready-to-use Ga-68 in clinical Positron Emission Tomography (PET) applications. The column adsorbent is the key component for the 68 Ge/ 68 Ga generator system. Therefore, several studies have been conducted to identify column materials with a stable and superior elution yield in an acidic eluent (0.1 N HCl solution). In this study, four different zirconium phosphates were synthesized with a particle size of 200–800 nm, pore-size of 55∼190 Å and surface area of 0.72–268 m 2 g −1 . Synthesized and studied amorphous zirconium phosphate (ZrP-1) exhibited excellent acid resistant properties for the 0.1 N HCl eluent and a large surface area of 268 m 2 g −1 . Amorphous ZrP-1 showed a good Ga-68 elution yield of 74% in 0.1 N HCl eluent accompanying extraordinary low breakthrough of Ge-68 (0.007%). [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09698043
- Volume :
- 118
- Database :
- Academic Search Index
- Journal :
- Applied Radiation & Isotopes
- Publication Type :
- Academic Journal
- Accession number :
- 120226256
- Full Text :
- https://doi.org/10.1016/j.apradiso.2016.09.025