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Pregnant women's cognitive appraisal of a natural disaster affects their children's BMI and central adiposity via DNA methylation: Project Ice Storm.

Authors :
Cao-Lei, Lei
Dancause, Kelsey N.
Elgbeili, Guillaume
Laplante, David P.
Szyf, Moshe
King, Suzanne
Source :
Early Human Development. Dec2016, Vol. 103, p189-192. 4p.
Publication Year :
2016

Abstract

We determined the extent to which DNA methylation mediates the effects of maternal cognitive appraisal of a natural disaster during pregnancy on offspring growth at age 13. Negative maternal cognitive appraisal predicted both lower BMI and central adiposity via DNA methylation of diabetes-related genes, suggesting a protective role of epigenetics. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03783782
Volume :
103
Database :
Academic Search Index
Journal :
Early Human Development
Publication Type :
Academic Journal
Accession number :
120141898
Full Text :
https://doi.org/10.1016/j.earlhumdev.2016.09.013