A paper-based microfluidic device with surface acoustic wave integrated in a printed circuit board.

A new method for fabricating a paper based microfluidic device in a printed circuit board is presented. The printed circuit board is hollowed out to form a pattern of paper channels. When a polydimethylsiloxane (PDMS) film is mounted on the bottom of the PCB, liquid PDMS is filled in the areas having been hollowed out, and solidified in a constant temperature oven. Paper pattern is then mounted on the solidified PDMS, while a piezoelectric device with an interdigital transducer is embedded into the PCB. At last, PDMS film is covered on the surface of paper channels. Microfluidic transportation and color development reaction are demonstrated in presented microfluidic platform. Results show paper channels and the piezoelectric device can be integrated into the printed circuit board, and surface acoustic wave can drive a microfluid to the paper channels for microfluidic analysis. [ABSTRACT FROM PUBLISHER]