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AIP1: a new player in TNF signaling.

Authors :
Guicciardi, M Eugenia
Gores, Gregory J
Source :
Journal of Clinical Investigation. 6/1/2003, Vol. 111 Issue 11, p1813-1815. 3p.
Publication Year :
2003

Abstract

Apoptosis signal-regulating kinase 1 (ASK1) is an upstream activator of JNK and p38 MAPK signaling cascades. Evidence now shows that the ASK1-interacting protein, AIP1, plays an important role in TNF-alpha-induced ASK1 activation by facilitating dissociation from its inhibitor. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00219738
Volume :
111
Issue :
11
Database :
Academic Search Index
Journal :
Journal of Clinical Investigation
Publication Type :
Academic Journal
Accession number :
119415234
Full Text :
https://doi.org/10.1172/jci200318911