A new dual-channel ratiometric fluorescent chemodosimeter for Cu2+ and its imaging in living cells.

Authors :: Fan, Zheng
Ye, Jia-Hai
Bai, Yang
Bian, Song
Wang, Xiaolong
Zhang, Wenchao
He, Weijiang
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Nov2016, Vol. 57 Issue 47, p5281-5285. 5p.
Publication Year :: 2016
Abstract: A new BODIPY derivative bearing hydrazone and hydrazide moieties was developed as an efficient dual-channel ratiometric fluorescence chemodosimeter 1 for Cu 2+ in neutral aqueous medium via Cu 2+ -mediated hydrolysis of C N bond in hydrazone unit. Confocal microscopy experiments have demonstrated that chemodosimeter 1 could also be used in live cells for the fast detection of Cu 2+ . [ABSTRACT FROM AUTHOR]

Subjects :: *FLUORESCENCE
*DOSIMETERS
*COPPER ions
*CELL imaging
*HYDROLYSIS
*CHEMICAL bonds
*HYDRAZONES

Language :: English
ISSN :: 00404039
Volume :: 57
Issue :: 47
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 119187793
Full Text :: https://doi.org/10.1016/j.tetlet.2016.10.050

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