丙泊酚和依托咪酯混合液持续泵注在无痛胃肠镜麻醉中的应用.

Objective: To investigate the effects of continuous Infusion of propofol and etomidate mixture in painless gastroscopy anesthesia. Methods: 120 patients who were treated with painless, selected gastrointestinal endoscopy were collected From September 2012 to February 2015 in our hospital and were equally divided into the treatment group of 60 patients and the control group of 60 patients. The patients in control group were received propofol auxiliary continuous infusion anesthesia, and the patients of the treatment group were received propofol and etomidate mixture assisted continuous infusion anesthesia. Results: All patients were completed the examination. The MAP and HR values at 2 min after the administration in two groups compared with before administration were statistically significant differences (P <0.05). but no difference was detectable between two groups. The above values for the remaining time in the group and between the two groups showed no significant difference (P> 0.05). The induction time and time away from the hospital in the treatment group were significantly less than that of the control group (P <0.05). while the examination time and wake time were no statistically significant between two groups (P> 0.05). After treatment, the nausea, vomiting, dizziness, skin itching and other complications in the treatment group were significantly less than those of the control group (P <0.05). Conclusions: Continuous infusion anesthesia of propofol and etomidate mixture in painless gastroscopy has less hemodynamic effect, and it can promote the effect of anesthesia and reduce the incidence of adverse reactions, worthy of promotion and applications in clinic. [ABSTRACT FROM AUTHOR]