抗VEGF药物联合532 激光治疗视网膜中央静脉阻塞的疗效分析.

Objective: To discuss the efficacy of anti VEGF drugs combined with 532 laser in treatment of central retinal vein occlusion. Methods: 60 patients with central retinal vein occlusion, 38-65 years old were selected and divided into two groups. The study group(31 cases) was given anti VEGF drugs combined with 532 laser, and the control group(29 cases) was adopted laser treatment. The vision and central macular thickness before therapy and 3 months after therapy, and the therapeutic outcome after 3 months therapy was observed. The efficacy of two different therapy were evaluated by these indexes. Results: After 3 months therapy, the rate of study group was obviously higher than that of control group (P<0.05). Compared with the vision before therapy, the vision became better after 3 months therapy in the study group. Besides, the improvement range in the study group was higher than that of the control group (P<0.05). After 3 months therapy, the vision of control group was improved, but there was no statistical significance between before and after treatment (P>0.05). Before therapy, there was no statistical significance on CMT between two groups (P>0.05), after 3 months therapy, the CMT in two groups was improved, and it was better in the study group (P<0.05). After therapy, no serious complications were detected in 3 months. Conclusions: The anti-VEGF drugs combined with 532 laser in treatment of the central retinal vein occlusion can significantly improve the vision of the patients, and obtain high effective rate and low accident rate of macular edema and neovascularization. The other complications will not be caused by this method. [ABSTRACT FROM AUTHOR]