A simple immunochemical technique for distinguishing melanocytes and melanophages in paraffin-embedded tissue.

Authors :: Fleming, M. G.
Bergfeld, W. F.
Source :: Journal of Cutaneous Pathology. Apr90, Vol. 17 Issue 2, p77-81. 5p.
Publication Year :: 1990
Abstract: We describe an immunoperoxidase technique for distinguishing melanocytes and melanophages in paraffin-embedded tissue. Two primary antibodies were used: anti-S100 and HAM-56, a monoclonal antibody directed against macrophages. In a variety of pigmented lesions, HAM-56 labelled melanophages while S100 labelled cells of melanocytic lineage. [ABSTRACT FROM AUTHOR]

Subjects :: *MELANOCYTES
*EPITHELIAL cells
*IMMUNOENZYME technique
*IMMUNOGLOBULINS
*PROTEIN binding
*IMMUNOLOGY technique

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