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Risk of Central Nervous System Tumors in Children Related to Parental Occupational Pesticide Exposures in three European Case-Control Studies.
- Source :
-
Journal of Occupational & Environmental Medicine . Oct2016, Vol. 58 Issue 10, p1046-1052. 7p. - Publication Year :
- 2016
-
Abstract
- Objective: The aim of this study was to assess the risk of childhood central nervous system (CNS) tumors associated with parental occupational pesticide exposure. Methods: We pooled three population-based case-control studies from France, Germany, and the United Kingdom. Cases were children below 15 years of age with CNS tumors; controls were matched by gender and age. A general population job-exposure matrix assessed parental occupational pesticide exposure. Logistic regressions estimated odds ratios (ORs) and 95% confidence intervals (CIs). Results: The study included 1361 cases and 5498 controls. Prevalence of maternal occupational pesticide exposure during pregnancy was low and no association with childhood CNS tumors was detected (OR 0.76, 95% Cl: 0.41 to 1.41). Around conception, OR for childhood CNS tumors associated with paternal occupational pesticide exposure was 0.71 (95% Cl: 0.53 to 0.95). Conclusion: Our results do not suggest a role of parental occupational pesticide exposure in the etiology of childhood CNS tumors. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10762752
- Volume :
- 58
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Journal of Occupational & Environmental Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 118799947
- Full Text :
- https://doi.org/10.1097/JOM.0000000000000852