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The Streptomyces coelicolor Polynucleotide Phosphorylase Homologue, and Not the Putative Poly(A) Polymerase, Can Polyadenylate RNA.
- Source :
-
Journal of Bacteriology . Dec2003, Vol. 185 Issue 24, p7273-7278. 6p. 3 Diagrams. - Publication Year :
- 2003
-
Abstract
- A protein containing a nucleotidyltransferase motif characteristic of poly(A) polymerases has been proposed to polyadenylate RNA in Streptomyces coelicolor (P. Bralley and G. H. Jones, Mol. Microbiol. 40:1155-1164, 2001). We show that this protein lacks poly(A) polymerase activity and is instead a tRNA nucleotidyltransferase that repairs CCA ends of tRNAs. In contrast, a Streptomyces coelicolor polynucleotide phosphorylase homologue that exhibits polyadenylation activity may account for the poly(A) tails found in this organism. [ABSTRACT FROM AUTHOR]
- Subjects :
- *STREPTOMYCES coelicolor
*PHOSPHORYLASES
*RNA
Subjects
Details
- Language :
- English
- ISSN :
- 00219193
- Volume :
- 185
- Issue :
- 24
- Database :
- Academic Search Index
- Journal :
- Journal of Bacteriology
- Publication Type :
- Academic Journal
- Accession number :
- 11856383
- Full Text :
- https://doi.org/10.1128/JB.185.24.7273-7278.2003