Back to Search Start Over

Fulminant liver failure resulting from massive hepatic infarction associated with hemolysis, elevated liver enzymes, and low platelets syndrome.

Authors :
Yoshihara, Masato
Mayama, Michinori
Ukai, Mayu
Tano, Sho
Kishigami, Yasuyuki
Oguchi, Hidenori
Source :
Journal of Obstetrics & Gynaecology Research. Oct2016, Vol. 42 Issue 10, p1375-1378. 4p. 1 Graph.
Publication Year :
2016

Abstract

Hepatic infarction is an extremely rare and fatal complication associated with hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome. It can develop into fulminant liver failure, which increases both maternal and neonatal mortality rates. A 34-year-old woman with no remarkable past medical history developed eclampsia after delivery at 40 weeks of gestation. Imaging indicated massive hepatic infarction and rupture followed by cardiac arrest and fulminant liver failure. Despite liver replacement therapy with plasma exchange and continuous hemodiafiltration, the patient gradually deteriorated with persistent bacterial infection until death at 98 days after delivery. The management of fulminant liver failure complicated with HELLP syndrome should be multidisciplinary. Liver transplantation, the only radical treatment for fulminant liver failure, is worth attempting, if applicable. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13418076
Volume :
42
Issue :
10
Database :
Academic Search Index
Journal :
Journal of Obstetrics & Gynaecology Research
Publication Type :
Academic Journal
Accession number :
118527612
Full Text :
https://doi.org/10.1111/jog.13042