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Genomic analysis of clonal origin of Langerhans cell histiocytosis following acute lymphoblastic leukaemia.
- Source :
-
British Journal of Haematology . Oct2016, Vol. 175 Issue 1, p169-172. 4p. 1 Chart, 1 Graph. - Publication Year :
- 2016
-
Abstract
- The article reports on a study that explored the origin and evolutionary process of the sequential relationship between Langerhans cell histiocytosis (LCH) and acute lymphoblastic leukemia (ALL). Topics discussed include the comprehensive genomic analysis of the dynamics of clonal architecture for one case and the genomic analysis performed for another 2 ALL cases that subsequently developed LCH. The derivation of LCH from a founding clone with genomic alterations common to ALL is mentioned.
Details
- Language :
- English
- ISSN :
- 00071048
- Volume :
- 175
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- British Journal of Haematology
- Publication Type :
- Academic Journal
- Accession number :
- 118324697
- Full Text :
- https://doi.org/10.1111/bjh.13841