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Outcomes associated with early removal versus retention of peripherally inserted central catheters after diagnosis of catheter-associated infections in neonates.
- Source :
-
Journal of Maternal-Fetal & Neonatal Medicine . Dec2016, Vol. 29 Issue 23, p4082-4087. 6p. - Publication Year :
- 2016
-
Abstract
- <bold>Objective: </bold>To compare clinical outcomes and hospital resource utilization of infants who had peripherally inserted central catheters removed early versus retained following diagnosis of central line-associated bloodstream infection.<bold>Study Design: </bold>In a single centre retrospective cohort study, we compared outcomes of infants who had peripherally inserted central catheters removed early versus retained after diagnosis of central line-associated bloodstream infection. Mortality, cardio-respiratory deterioration, use of blood products and antibiotics were compared between groups.<bold>Results: </bold>Over a 10-year period, of the 119 eligible infants, 38 had peripherally inserted central catheters removed early and 81 had catheters retained after diagnosis of central line-associated bloodstream infection. Baseline demographics, illness severity at onset of sepsis and distribution of organisms were similar between the groups. Infants in "catheter-retained" group required longer antibiotic usage (17 ± 9 versus 13 ± 6 days; p = 0.025) and more frequent sequential positive blood cultures [31/81 (47%) versus 8/38 (22%), p = 0.014). Infants with Gram-negative bacteremia demonstrated higher mortality when catheters were retained [43% (9/21) versus 7% (1/14); p = 0.028].<bold>Conclusions: </bold>Retaining peripherally inserted central catheters after diagnosis of central line-associated bloodstream infection was associated with longer duration of bacteremia and prolonged exposure to systemic antibiotics as well as increased mortality in Gram-negative bacteremia. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ANTIBIOTICS
*CATHETERS
*COMPARATIVE studies
*GESTATIONAL age
*INTRAVENOUS catheterization
*RESEARCH methodology
*MEDICAL cooperation
*NONPARAMETRIC statistics
*RESEARCH
*TIME
*EVALUATION research
*RETROSPECTIVE studies
*SEVERITY of illness index
*MEDICAL device removal
*CENTRAL venous catheters
*ODDS ratio
*CATHETER-related infections
*DIAGNOSIS
*THERAPEUTICS
Subjects
Details
- Language :
- English
- ISSN :
- 14767058
- Volume :
- 29
- Issue :
- 23
- Database :
- Academic Search Index
- Journal :
- Journal of Maternal-Fetal & Neonatal Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 118307285
- Full Text :
- https://doi.org/10.3109/14767058.2016.1157578