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Health outcomes of neonates with osteogenesis imperfecta: a cross-sectional study.
- Source :
-
Journal of Maternal-Fetal & Neonatal Medicine . Dec2016, Vol. 29 Issue 23, p3889-3893. 5p. - Publication Year :
- 2016
-
Abstract
- <bold>Objective: </bold>To assess at-birth health outcomes of neonates with osteogenesis imperfecta (OI).<bold>Study Design: </bold>A total of 53 women who self-reported having had at least one child with OI completed the survey. We evaluated pregnancy length, neonatal intensive care unit (NICU) usage, at-birth complications, and the child's clinical information including OI type, height and weight.<bold>Results: </bold>Information was gathered on a total of 77 children (60 type I, 4 type III and 13 type IV). Health conditions reported at birth included breech presentation (24%), prematurity (27%), fracture (18%), bone deformity (18%) and respiratory problems (22%). Approximately 31% (nā=ā24) received NICU care. There was a significant association between younger maternal age, preterm delivery and NICU admission.<bold>Conclusion: </bold>Our findings suggest that newborns with OI appear to be at high risk of skeletal disorders, preterm delivery and breech presentation. Younger maternal age and preterm delivery seem to be strong predictors of the need for NICU care. Our data suggest that pregnant women with OI younger than 20 years of age may benefit from added clinical supervision in anticipation of adverse effects on their child. [ABSTRACT FROM AUTHOR]
- Subjects :
- *OSTEOGENESIS imperfecta
*PREMATURE labor
*NEONATAL intensive care
*MATERNAL age
*SKELETAL dysplasia
*AGE distribution
*BIRTH weight
*BREECH delivery
*BONE fractures
*PREMATURE infants
*MUSCULOSKELETAL system abnormalities
*PRENATAL care
*PRENATAL diagnosis
*RESPIRATORY diseases
*NEONATAL intensive care units
*ACQUISITION of data
*CROSS-sectional method
*DISEASE complications
Subjects
Details
- Language :
- English
- ISSN :
- 14767058
- Volume :
- 29
- Issue :
- 23
- Database :
- Academic Search Index
- Journal :
- Journal of Maternal-Fetal & Neonatal Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 118280763
- Full Text :
- https://doi.org/10.3109/14767058.2016.1151870