Free-Radical Triggered Ordered Domino Reaction: An Approach to C-C Bond Formation via Selective Functionalization of α-Hydroxyl-(sp³)C-H in Fluorinated Alcohols.

A free-radical mediated highly ordered radical addition/cyclization/(sp³)C-C(sp³) formation domino reaction is developed. Three new C-C bonds are formed one by one in a mixed system. Furthermore, it represents the first example of cascade C-C bond formation via selective functionalization of α-hydroxyl-C(sp³)-H in fluorinated alcohols. [ABSTRACT FROM AUTHOR]