Three successful deliveries involving a woman with congenital afibrinogenaemia - conventional fibrinogen concentrate infusion vs. 'as required' fibrinogen concentrate infusion based on changes in fibrinogen clearance -.

A case study is presented on three successful deliveries involving a pregnant woman with congenital afibrinogenaemia - conventional fibrinogen concentrate infusion vs. 'as required' fibrinogen concentrate infusion based on changes in fibrinogen clearance. Topics include the case being the first in the world in which a pregnancy involving a patient with congenital afibrinogenaemia was successfully managed and 'as required' fibrinogen replacement found to be easy to manage.