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A Single Mutation Asp229...Ser Confers upon Gs... the Ability To Interact with Regulators of G...

Authors :
Natochin, Michael
Artemyev, Nikolai O.
Source :
Biochemistry. 09/29/98, Vol. 37 Issue 39, p13776. 5p.
Publication Year :
1998

Abstract

Presents a study investigating the possibility of generating an interaction between Gs... and (regulator of G protein signaling (RGS) proteins by substituting Gs... Asp229 with Ser and replacing the potential Gs... Asp229 contact residues in RGS16, Glu129 and Asn131, by Ala and Ser, respectively. Methodology used to conduct the study; Expression of the Gs... Asp229 Ser mutant; Findings of the study.

Subjects

Subjects :
*G proteins

Details

Language :
English
ISSN :
00062960
Volume :
37
Issue :
39
Database :
Academic Search Index
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
1177997
Full Text :
https://doi.org/10.1021/bi981155a