SUBJEKTIVNĚ VNÍMANÁ KVALITA ŽIVOTA DOSPÍVAJÍCÍCH A MLADÝCH DOSPĚLÝCH PO LÉČBĚ DĚTSKÉHO ONKOLOGICKÉHO ONEMOCNĚNÍ V DLOUHODOBÉ PERSPEKTIVĚ: PŘEDBĚŽNÉ VÝSLEDKY LONGITUDINÁLNÍ STUDIE QOLOP

Objectives. The study deals with subjective quality of life of childhood cancer survivors. Sample and setting. Sample consisted of 65 adolescents and young adults (33 girls) aged 12-25 years (mean age = 17.54). Quality of life was assessed using the Minneapolis-Manchester Quality of Life Instrument (MMQL) and Children's Depression Inventory (CDI) twice: for the first time 1-11 years after treatment, for the second time after a time interval of another 1-6 years. Hypotheses. The decline in subjective quality of life between two measurements was expected. Statistical analysis. The levels of the measured characteristics were compared using a paired t-test, effect size was expressed by Cohen's D. Relationships between measurements were analyzed using the Pearson correlation coefficient. Results. There were no significant differences in the level of the characteristics observed in the first and second measurements. Life satisfaction declined at the time of the second measurement, however, its level was comparable to healthy controls and the decline was not statistically significant when adjusted by Bonferroni correction. Relatively close relationships between the first and second measurements in MMQL were found. In the case of CDI, the relationships were looser as compared to MMQL, which can probably be explained by the low variability of CDI scores. Study limitation. So far, a relatively low number of people was interviewed in the second wave of the longitudinal study. Moreover, sample is considerably heterogeneous and division into subsamples will be needed for further analyses after completing data collection. [ABSTRACT FROM AUTHOR]