甲状腺超声影像和数据报告系统在不同性别和年龄甲状腺结节患者中的诊断价值

Objective To explore the application value of Thyroid Imaging Reporting and Data System (TI-RADS) stratification in diagnosing thyroid nodules in respect of the effect of age and gender. Methods A total of 684 patients with thyroid nodules, including 118 males and 566 females, were stratified into subgroups according to their age and gender, and the results of TI-RADS evaluation were compared with their pathological diagnosis. Results The sensitivity, specificity, and AUC of TI-RADS grading for malignant thyroid nodules in the males was 84.7%, 66.7%, and 0.803 (95% CI 0.709-0.897), respectively. In the females, the sensitivity and specificity were 80.8% and 65.0%, respectively, with an AUC of 0.812 (95% CI 0.758-0.849). There was no statistically significant difference between genders when using TI-RADS to determine the nature of thyroid nodules (P>0.05). In the patients aged 26-35 years, the sensitivity, specificity and AUC of TI-RADS classification for malignant thyroid nodules were 85.4%, 90.0%, and 0.915 (95% CI 0.818-0.987), respectively. In the patients aged 36-45 years, the sensitivity and specificity of TI-RADS classification for malignant thyroid nodules were 84.4% and 78.1%, respectively, with an AUC of 0.898 (95% CI 0.842-0.953). In the patients aged 46-55 years, the corresponding parameters were 79.7%, 71.4% and AUC 0.822 (95% CI 0.789-0.925), respectivey, while in those aged 56-65 years, the corresponding data were 75.6%, 60.0%, and AUC 0.729 (95% CI 0.576-0.785), respectively. The ROC curve of patients aged 56-65 years was statistically significantly different from those of patients aged 26-35, 36-45 and 46-55 years (P<0.05 for all). Conclusions Patient gender has no significant effect on the results of TI-RADS classification, but age of the patients does. The age factor should be considered during ultrasound diagnosis of thyroid nodules using TI-RADS classification. [ABSTRACT FROM AUTHOR]