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Survival outcomes scores ( SOFT, BAR, and Pedi- SOFT) are accurate in predicting post-liver transplant survival in adolescents.

Authors :
Conjeevaram Selvakumar, Praveen Kumar
Maksimak, Brian
Hanouneh, Ibrahim
Youssef, Dalia H.
Lopez, Rocio
Alkhouri, Naim
Source :
Pediatric Transplantation. Sep2016, Vol. 20 Issue 6, p807-812. 6p.
Publication Year :
2016

Abstract

SOFT and BAR scores utilize recipient, donor, and graft factors to predict the 3-month survival after LT in adults (≥18 years). Recently, Pedi- SOFT score was developed to predict 3-month survival after LT in young children (≤12 years). These scoring systems have not been studied in adolescent patients (13-17 years). We evaluated the accuracy of these scoring systems in predicting the 3-month post- LT survival in adolescents through a retrospective analysis of data from UNOS of patients aged 13-17 years who received LT between 03/01/2002 and 12/31/2012. Recipients of combined organ transplants, donation after cardiac death, or living donor graft were excluded. A total of 711 adolescent LT recipients were included with a mean age of 15.2±1.4 years. A total of 100 patients died post- LT including 33 within 3 months. SOFT, BAR, and Pedi- SOFT scores were all found to be good predictors of 3-month post-transplant survival outcome with areas under the ROC curve of 0.81, 0.80, and 0.81, respectively. All three scores provided good accuracy for predicting 3-month survival post- LT in adolescents and may help clinical decision making to optimize survival rate and organ utilization. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13973142
Volume :
20
Issue :
6
Database :
Academic Search Index
Journal :
Pediatric Transplantation
Publication Type :
Academic Journal
Accession number :
117573547
Full Text :
https://doi.org/10.1111/petr.12770