七氟醚与丙泊酚复合麻醉对老年骨科患者术后认知功能和清醒质量的影响

Objective To observe the influence of sevoflurane and diprivan combined anesthesia on postoperative cogni-tive function and sober quality in elderly orthopedic patients. Methods 90 elderly patients undergoing orthopedic surgery under general anesthesia from January 2011 to January 2015 were selected and divided into the sevoflurane combined anesthesia group(group S) and the diprivan combined anesthesia group(group P)according to different anesthetic ways, 45 cases in each group.The general surgical conditions(operation time, anesthesia time, amount of bleeding, eye opening time, extubating time, etc.) were observed in the two groups. The patients′ cognitive function at 24, 48, 72 h after surgery were compared by using mini-mental state examination(MMSE). Results The operation time, anesthesia time, amount of bleeding, eye opening time and extubating time had no statistically significant differences between the two groups(P>0.05). The MMSE scores after operation in the two groups were dropped. The MMSE score at 48 h after surgery in the group S was(27.15±0.86) points, which was significantly higher than(26.55±0.87)points in the group P, the difference was statistical significance(t=3.29, P<0.05). Conclusion Sevoflurane and diprivan combined anesthesia can cause the declining of postoperative cognitive function in elderly orthopedic patients, but which can recover within 3 d. Sevoflurane combined anesthesia can early recover the patient′s cognitive function. Both anesthetic methods have no obvious influence on postoperative sober quality. [ABSTRACT FROM AUTHOR]