Radiotherapy in management of brain metastases.

Nearly half of all cancer patients unavoidably experience brain metastases (BM) somewhere during their disease course. Current treatment approaches include neurosurgery, wholebrain radiotherapy (WBRT), stereotactic radiosurgery (SRS), chemotherapy, and targeted agents which may be utilized either individually or as any combination, depending on the anticipated patient's prognosis. Radiotherapy, directed to whole-brain contents or exclusively the BMs, is the cornerstone of palliative management of patients with BM. This present review manuscript will particularly focus on the use of two well-established effective palliative radiotherapy modalities and their comparative effectiveness, namely the WBRT and SRS. [ABSTRACT FROM AUTHOR]