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Future prospects of antibacterial metal nanoparticles as enzyme inhibitor.

Authors :
Ahmed, Khan Behlol Ayaz
Raman, Thiagarajan
Veerappan, Anbazhagan
Source :
Materials Science & Engineering: C. Nov2016, Vol. 68, p939-947. 9p.
Publication Year :
2016

Abstract

Nanoparticles are being widely used as antibacterial agents with metal nanoparticles emerging as the most efficient antibacterial agents. There have been many studies which have reported the mechanism of antibacterial activity of nanoparticles on bacteria. In this review we aim to emphasize on all the possible mechanisms which are involved in the antibacterial activity of nanoparticles and also to understand their mode of action and role as bacterial enzyme inhibitor by comparing their antibacterial mechanism to that of antibiotics with enzyme inhibition as a major mechanism. With the emergence of widespread antibiotic resistance, nanoparticles offer a better alternative to our conventional arsenal of antibiotics. Once the biological safety of these nanoparticles is addressed, these nanoparticles can be of great medical importance in our fight against bacterial infections. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09284931
Volume :
68
Database :
Academic Search Index
Journal :
Materials Science & Engineering: C
Publication Type :
Academic Journal
Accession number :
117437626
Full Text :
https://doi.org/10.1016/j.msec.2016.06.034