Zinc-Catalyzed Synthesis of 2-Alkenylfurans via Cross-Coupling of Enynones and Diazo Compounds.

The title transformation involves an intramolecular cyclization of enynones (I) followed by coupling with the diazo compound (II) and leads to the formation of a series of new C--O and C--C double bonds. Relevant CF3-substituted 2-vinylfuran derivatives (VII)/(VIII) are also accessed by this method using in situ generated trifluoromethyl diazomethane (VI). [ABSTRACT FROM AUTHOR]