Two new double mutant alleles of the F7 gene and a literature review on alleles with two mutations in FVII deficiency.

The article discusses a literature review on alleles with two mutations in inherited factor VII (FVII) deficiency, and the two new double mutant alleles of the F7 gene. Topics include the molecular analysis of the gene, the common F7 polymorphisms, and the double mutant alleles of disease genes, particularly in small genes, like the F7 gene.