l-SPY 2 — Toward More Rapid Progress in Breast Cancer Treatment.

The author discusses the Investigation of Serial Studies to Predict Your Therapeutic Response through Imaging and Molecular Analysis 2 trial (I-SPY 2 TRIAL) for screening new cancer treatment. Topics include the comparison between the use of chemotherapy, neratinib and trastuzumab as a treatment for patient with HER-2 protein-breast cancer, the potential toxic effects of trastuzumab, pertuzumab, and neratinib when added to the chemotherapy, and the neoadjuvant therapy in cancer treatment.