循环miRNA在肝MK疾病诊断屮的研究进展.

MicroRNAs ( miRNAs) ait involved in ihe pathological and physiological process of life activities, and some of them exist stably and abundantly in serum, plasma, and other body fluids. Previous studies have indicated that there are significant differences in the expression patterns of circulating miRNAs between patients with viral hepatitis, liver fibrosis, liver cirrhosis, hepatocellular carcinoma, drug -induced hepatitis, and other hepatobiliary diseases at different disease stages. Among these circulating miRNAs. some can act as novel noninvasive biomarkers for the early diagnosis, disease progression, and prognostic evaluation of related diseases. The latest research advances in circulating miRNAs for the diagnosis of hepatobiliary diseases are reviewed. [ABSTRACT FROM AUTHOR]