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Genetic control and regulatory mechanisms of succinoglycan and curdlan biosynthesis in genus Agrobacterium.

Authors :
Wu, Dan
Li, Ang
Ma, Fang
Yang, Jixian
Xie, Yutong
Source :
Applied Microbiology & Biotechnology. Jul2016, Vol. 100 Issue 14, p6183-6192. 10p.
Publication Year :
2016

Abstract

Agrobacterium is a genus of gram-negative bacteria that can produce several typical exopolysaccharides with commercial uses in the food and pharmaceutical fields. In particular, succinoglycan and curdlan, due to their good quality in high yield, have been employed on an industrial scale comparatively early. Exopolysaccharide biosynthesis is a multiple-step process controlled by different functional genes, and various environmental factors cause changes in exopolysaccharide biosynthesis through regulatory mechanisms. In this mini-review, we focus on the genetic control and regulatory mechanisms of succinoglycan and curdlan produced by Agrobacterium. Some key functional genes and regulatory mechanisms for exopolysaccharide biosynthesis are described, possessing a high potential for application in metabolic engineering to modify exopolysaccharide production and physicochemical properties. This review may contribute to the understanding of exopolysaccharide biosynthesis and exopolysaccharide modification by metabolic engineering methods in Agrobacterium. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
01757598
Volume :
100
Issue :
14
Database :
Academic Search Index
Journal :
Applied Microbiology & Biotechnology
Publication Type :
Academic Journal
Accession number :
116285701
Full Text :
https://doi.org/10.1007/s00253-016-7650-1