483 例儿童扁桃体腺样体肥大分离菌的分布和药敏特征.

Objective: To explore the distribution of isolated bacteria and its drug susceptibility feature in culture of tissues from tonsil adenoidectomy in children, and provide instructions for the clinical prevention and treatment. Methods: 483 cases of adenoid tonsil samples were collected for bacterial culture, the main isolated bacteria and drug susceptibility feature were analyzed. Results: The positive rate of pathogenic bacteria was 66.43% and 52.88% for tonsil and adenoid samples respectively. There were four main bacteria,including staphylococcus aureus, haemophilus influenze, streptococcus pneumoniae, group A streptococcus, which accounted for20.71%, 15.11%, 10.97%, 6.42% respectively. S. aureus had a resistant rate of 82% to penicillin, of which 21% isolates were MRSA. While for h. influenzae, the positive rate of beta-lactamase was 30.92%, with a high resistant rate of 50.69% and 30.14% to trimethoprim-sulfamethoxazole and ampicillin respectively. Streptococcus pneumoniae had a resistant rate of 32.08% to penicillin, with a high resistant rate of 81.13%, 79.25% and 69.81% to erythromycin, tetracycline, trimethoprim-sulfamethoxazole respectively. For group A streptococcus, no resistance to penicillin was detected, with a high resistant rate of 83.87%, 77.42% and 58.06% for erythromycin,clindamycin, tetracycline. Conclusions: The main isolated potential pathogenic bacteria included s. aureus, h. influenzae, streptococcus pneumoniae, group A streptococcus. There were obvious differences of the drug resistance among them, which could afford good instructions for its clinical prevention and treatment of pediatric tonsil and adenoid infection. [ABSTRACT FROM AUTHOR]